falciparum can also complicate detection of nonfalciparum species ( 3, 17). Nonfalciparum malaria parasite densities are often low, and most infected persons might not seek care. lactate dehydrogenase (LDH) or histidine-rich protein 2 (HRP2)–based rapid diagnostic tests (RDTs), lack sensitivity to detect nonfalciparum species ( 11, 17). Field diagnostic methods, such as microscopy and pan– Plasmodium spp. However, comprehensive surveys of nonfalciparum malaria in sub-Saharan Africa have been infrequent because detection of those species remains challenging ( 11, 17). falciparum prevalence in East Africa might be associated with increasing nonfalciparum infections ( 17– 20). ovale infections have been mostly described in travelers and have been associated with severe infection in case reports ( 16).ĭeclining P. vivax can cause severe anemia, pregnancy-related complications, and death after recurrent infections, but infections in sub-Saharan Africa are infrequent ( 13– 15). malariae has been associated with increased risk for anemia ( 10) and other complications, such as chronic nephrotic syndrome ( 11, 12). falciparum ( 9), nonfalciparum species can still cause disease. Although the clinical prevalence of nonfalciparum malaria in sub-Saharan Africa is dwarfed by P. falciparum (hereafter nonfalciparum) malaria species, such as P. National surveys conducted by ministries of health throughout Africa regularly assess Plasmodium falciparum prevalence ( 2) however, little is known about the prevalence and geographic distribution of non– P. Sub-Saharan Africa harbors 95% of the global malaria burden ( 1). ovale infections exists among schoolchildren in Tanzania, underscoring the need for detection and treatment strategies that target non– P. vivax was detected mostly in northern and eastern regions. malariae infections were predominantly (73%) co-infections with P. ovale infections were single-species infections, and 35% of those were detected in low malaria endemic regions. ovale infections had low parasite densities 64% of P. by performing PCR on dried blood spots collected within 8 regions of Tanzania during 2017. We determined prevalence and geographic distribution of 4 Plasmodium spp. ![]() Achieving malaria elimination requires considering both Plasmodium falciparum and non– P.
0 Comments
Leave a Reply. |